Protein or peptide name: | MgrB |
Chromosome: | str. K-12 substr. MG1655, complete genome |
Protein or peptide start site: | 1908623 |
Protein or peptide end site: | 1908766 |
ncRNA start site: | 1908623 |
ncRNA end site: | 1908766 |
Genome Browser: | NA |
Protein or peptide sequence: | MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW |
Protein or peptide length: | 47aa |
ncRNA type: | ncRNA |
ncRNA name: | mgrB |
Entrez ID: | 946351 |
Experimental species: | Escherichia coli |
Experimental techniques: | Fluorescence microscopy/Western blotting |
Experimental sample (cell line and/or tissue): | E. coli |
Description: | We found that deletion of mgrB (yobG), which encodes a 47 amino acid peptide, results in a potent increase in PhoP-regulated transcription. |
Subcellular location: | inner membrane |
Function: | MgrB is a broadly conserved membrane peptide that is a critical mediator of negative feedback in the PhoQ/PhoP circuit. |
Title of paper: | Feedback inhibition in the PhoQ/PhoP signaling system by a membrane peptide |
PMID: | 20041203 |
Year of publication: | 2009 |