Protein or peptide name:MgrB
Chromosome:str. K-12 substr. MG1655, complete genome
Protein or peptide start site:1908623
Protein or peptide end site:1908766
ncRNA start site:1908623
ncRNA end site:1908766
Genome Browser:NA
Protein or peptide sequence:MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQFIPW
Protein or peptide length:47aa
ncRNA type:ncRNA
ncRNA name:mgrB
Entrez ID:946351
Experimental species:Escherichia coli
Experimental techniques:Fluorescence microscopy/Western blotting
Experimental sample (cell line and/or tissue):E. coli
Description:We found that deletion of mgrB (yobG), which encodes a 47 amino acid peptide, results in a potent increase in PhoP-regulated transcription.
Subcellular location:inner membrane
Function:MgrB is a broadly conserved membrane peptide that is a critical mediator of negative feedback in the PhoQ/PhoP circuit.
Title of paper:Feedback inhibition in the PhoQ/PhoP signaling system by a membrane peptide
PMID:20041203
Year of publication:2009